·         Represents a major step in the mission of Actimed to bring the first globally approved cancer cachexia product to patients in need 

Bengaluru – 20^th November 2025 : Actimed Therapeutics Ltd (“Actimed”), a UK based clinical stage specialty pharmaceutical company focused on bringing innovation to the treatment of cancer cachexia and other muscle wasting disorders, today announces that it has entered into a licensing agreement with Mankind Pharma Limited (“Mankind”), one of India’s leading innovative pharmaceutical companies and a shareholder in Actimed, granting Mankind exclusive rights to develop and commercialise Actimed’s products for use in the treatment and/or prevention of cachexia in India and South Asian territories.

Under the agreement, Mankind gains exclusive territorial product rights in the Indian subcontinent, comprising India, Bangladesh, Bhutan, Nepal, Sri Lanka and Myanmar. The license covers Actimed’s patents, know-how and any future related patents, enabling Mankind to develop, manufacture and commercialise the products in the territory under its own trademarks. The agreement is limited to the field of use in the treatment and/or prevention of cachexia, and Mankind will be responsible for all associated development, manufacturing and sales and marketing costs.

The licensed products include those developed based on Actimed intellectual property and patents within the field of use, including the Actimed programmes for S-pindolol benzoate (ACM-001.1), which Actimed plans to take into the Phase 2b/3 clinical development stage for cancer cachexia. Subject to successful completion and regulatory approvals, the product will be commercialised by Mankind in the above-mentioned territories. The Commercial terms of the agreement are not being disclosed.

Atish Majumdar, Senior President (Sales & Marketing) at Mankind Pharma and Non-Executive Director, Actimed, added: “Mankind has been a long-term supporter and shareholder of Actimed, and we are proud to deepen our partnership through this strategic licensing agreement. This collaboration reflects our shared commitment to advancing innovative therapies and improving the lives of patients affected by cachexia across the Indian subcontinent. We have strong confidence in Actimed’s vision, leadership, and development expertise, and we are proud to partner with them on this important journey.”

Robin Bhattacherjee, Actimed CEO, commented: “We are delighted to enter into this agreement with Mankind. Cachexia is a debilitating condition for which there are currently no globally approved therapies. By combining the Actimed cachexia product pipeline with Mankind’s strong development and commercial capabilities in its key markets, we are taking a major step forward in our aim to deliver meaningful treatment options to cachexia patients globally.”

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Developed at the Mankind Research Centre, MKP11093 has shown strong results in preclinical studies with a promising safety and selectivity profile. The molecule works by targeting JAK-1—one of the key enzymes in the JAK family (JAK1, JAK2, JAK3, TYK2). By blocking these enzymes, MKP11093 disrupts the JAK/STAT signaling pathway and reduces the activity of several pro-inflammatory cytokines. This makes it a unique treatment candidate with the potential to deliver better outcomes in autoimmune diseases.

Speaking on the development, Mr. Arjun Juneja, Chief Operating Officer, Mankind Pharma, said: “At Mankind Research Centre, we are advancing a pipeline of innovative therapies across high-burden therapeutic areas where significant unmet needs exist. The development of MKP11093 is a major milestone in this effort, representing our endeavour to deliver a best-in-class JAK inhibitor that maximises therapeutic potential while addressing the safety concerns associated with conventional approaches. This achievement underscores our broader innovation agenda at Mankind Pharma, powered by the expertise of over 730 scientists and supported by an expanding R&D ecosystem. By integrating advanced technologies, we are accelerating discovery and development to bring forward differentiated treatments that can make a meaningful impact on patients’ lives — with a strong focus on ensuring that such innovations are accessible and affordable to those who need them most, both in India and globally.”

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Launched across YouTube and Meta platforms, Gas-O-Fast’s latest campaign proudly positions it as the Asli Indian Solution. Rooted in the country’s love for bold, flavour-packed food, the campaign champions jeera, India’s time-tested remedy.

Link to the campaign video: https://youtu.be/-vS0VfGZ8Ns?si=U87jjlRq1G1ho3iO 

Joy Chatterjee, Vice President, Sales and Marketing Head, Consumer Business Unit, Mankind Pharma, commented: “This Independence Day, we are urging Indians to ‘Be Vocal for Local Brands’ and reflect on a simple truth- if our food is proudly desi and our acidity is undeniably desi, our relief should be just as desi.” Gas-O-Fast isn’t just about treating acidity; it’s about reclaiming our digestive independence with time-tested Indian ingredients like jeera, delivered in a modern, fast-acting format. In line with the ‘Make in India’ vision, we are championing solutions that are made by Indians, for Indians, and rooted in our own wisdom.”

Gas-O-Fast’s Independence Day campaign goes beyond traditional celebrations, inspiring Indians to choose Made in India solutions for their healthcare needs. Celebrating the nation’s love for bold, spicy flavours, the campaign champions Gas-O-Fast as the natural, Indian solution for home-grown digestive issues. With the time-tested goodness of jeera in a modern, fizz-powered format, Gas-O-Fast stands out as an antacid that doesn’t just treat the Indian gut, it understands and celebrates it.

At the heart of Gas-O-Fast’s formulation is jeera (cumin), a time-tested Indian remedy for digestive issues. The brand brings this traditional ingredient back to the forefront in a fast, fizzy, modern format, reclaiming it as the smart choice for contemporary Indians who want effective relief rooted in Indian wisdom.

“Jeera isn’t just a spice in Indian kitchens, it’s been our digestive companion for centuries,” added Mr. Chatterjee. “We’ve simply modernized this age-old remedy for today’s fast-paced lifestyle while maintaining its desi essence.” 

The complete Independence Day campaign film is now live on Gas-O-Fast’s official YouTube channel and across its social media platforms on Meta.

Gas-O-Fast remains committed to offering effective digestive relief that’s proudly rooted in India. As a Make in India product, it brings together time-tested Indian ingredients like jeera with modern convenience to meet the unique needs of Indian consumers who enjoy the country’s rich and spicy food culture.

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Link to the video campaign: https://www.youtube.com/watch?v=Oe2hOqlWXJs

The sobering reality in India is that for every 10 lakh Indians, less than 1% pledge to donate their organs to those in need. This significant gap between demand and supply has resulted in thousands of patients waiting for life-saving organ transplants, including kidneys, liver, eyes, and hearts.

Rajeev Juneja, Vice-Chairman and Managing Director, Mankind Pharma shared, “At Mankind Pharma, we believe that collective action has the power to transform healthcare outcomes. Our organ donation awareness campaign reflects our steadfast commitment to tackling one of India’s most pressing health challenges. Registering as an organ donor is a simple step, yet it holds the power to change and even save multiple lives. By this initiative, we aim to engage with our wider community and honour the compassionate individuals who choose to give the ultimate gift of life. We call upon every Indian to take this pledge and be part of a legacy that continues long after our time.”

On this initiative by Mankind, Dr Kanika Rastogi, Deputy Director – National Organ and Tissue Transplant Organization (NOTTO) commented, “India’s low organ donation rate has left thousands of patients waiting for a second chance at life. This campaign by Mankind Pharma is an important step in addressing this shortage. By creating awareness and simplifying the process of registration, we can inspire more people to pledge. Just one donor has the power to save up to eight lives, a gift of hope that truly extends beyond our own.”

Medical experts – Dr. A.K. Bhalla (Sir Ganga Ram Hospital) and Dr. Neelam Mohan (Medanta) – addressed the humanitarian importance of organ donation, dispelled myths and highlighted the vast demand-supply gap in organ availability. They lauded Mankind Pharma’s campaign and reiterated that such social awareness initiatives are vital to spreading the message on the need to donate organs.

The video campaign featuring Amitabh Bachchan serves as a clarion call to the nation, urging Indians to make an invaluable promise that can save the lives of many. By leveraging the megastar’s influential voice and Mankind Pharma’s commitment to healthcare advancement, the initiative seeks to create a lasting impact on public consciousness about the importance of organ donation.

This World Organ Donation Day, Mankind Pharma calls upon every Indian to consider the profound impact they can have on society by taking the simple yet meaningful step of registering as an organ donor. The campaign reinforces that the legacy of giving extends far beyond one’s lifetime, creating ripples of hope and healing for generations to come.

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